Current Knowledge and Clinical Application of Brain Imaging in Alzheimer's Disease
10.4306/jknpa.2018.57.1.12
- Author:
Dong Woo KANG
1
;
Hyun Kook LIM
Author Information
1. Department of Psychiatry, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
- Publication Type:Review
- Keywords:
Alzheimer's disease;
Brain imaging;
Visual rating scale;
Magnetic resonance imaging;
Positron emission tomography
- MeSH:
Alzheimer Disease;
Atrophy;
Brain;
Cognition Disorders;
Diagnosis, Differential;
Functional Neuroimaging;
Humans;
Magnetic Resonance Imaging;
Neuroimaging;
Positron-Emission Tomography;
Prognosis;
Weights and Measures
- From:Journal of Korean Neuropsychiatric Association
2018;57(1):12-22
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Alzheimer's disease (AD) is a debilitating syndrome with cognitive decline and impairment in daily activities. Although clinical assessment forms the basis for diagnosing AD, structural and functional brain imaging tools have been known to enhance accuracy of differential diagnosis and prognosis prediction by presenting structural and functional signatures for AD. Associated with the important role of brain imaging in diagnosing and treating AD, brain imaging has been recommended in the current diagnostic guidelines of AD. Visual rating scales, a cost-effective diagnostic tool, have been known to assess atrophy and functional changes in patients with cognitive impairment as accurate as quantitative assessment. In this regard, visual rating scales for brain imaging interpretation could be useful in clinical settings. In this review, we interpret structural and functional brain imaging results with standardized visual rating scales, and review recent findings concerning brain imaging tools for differential diagnosing and predicting prognosis of AD.
