New Potential Therapies for Chronic Hepatitis B
10.4166/kjg.2019.74.5.267
- Author:
Sun Hong YOO
1
;
Jung Hyun KWON
Author Information
1. Department of Internal Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea. doctorkwon@catholic.ac.kr
- Publication Type:Review
- Keywords:
Hepatitis B virus;
Therapeutics
- MeSH:
Antiviral Agents;
Carcinoma, Hepatocellular;
Hepatitis B Surface Antigens;
Hepatitis B virus;
Hepatitis B, Chronic;
Hepatitis, Chronic;
Inflammation;
Interferons;
Liver;
Liver Cirrhosis
- From:The Korean Journal of Gastroenterology
2019;74(5):267-273
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A HBV infection is a dynamic disease and long-term liver inflammation contributes to the development of liver cirrhosis and hepatocellular carcinoma. Currently available nucleos(t)ide analogues and pegylated interferon are effective in inhibiting HBV replication but rarely achieve HBsAg clearance. The present article introduces a new definition of HBV cure and several emerging therapies for HBV cure, including direct acting antivirals and immune modulatory antivirals.
