The roles of placenta-derived miRNAs in the occurrence and development of preeclampsia and their clinical values
10.3760/cma.j.issn.1009-9158.2019.07.015
- VernacularTitle:胎盘来源的miRNAs在子痫前期发生发展的作用及临床价值
- Author:
Yuping DUAN
1
;
Liansheng JIANG
;
Li LI
;
Qian LI
Author Information
1. 上海市第一人民医院宝山分院医学检验科 200940
- Keywords:
Pre-eclampsia;
Placenta;
microRNAs
- From:
Chinese Journal of Laboratory Medicine
2019;42(7):575-580
- CountryChina
- Language:Chinese
-
Abstract:
Preeclampsia (PE) is a serious disease that threatens the health of maternal and newborn. However, the etiology and pathogenesis of PE remains elusive. Micro-RNA, a class of noncoding small single stranded RNA, plays an important role in the physiologic and pathophysiologic process of PE. In recent years, some researchers classified the placenta-derived miRNAs and investigated their roles in the occurrence of PE and their potential value in the PE early diagnosis. These findings are summarized in the review.
