Paying attention to the study of proteomics in muscular diseases
10.3760/cma.j.issn.1006-7876.2019.06.001
- VernacularTitle:关注蛋白质组学在肌肉病的研究
- Author:
Chuanqiang PU
1
;
Yutong ZHANG
Author Information
1. 解放军总医院神经内科
- Keywords:
Proteomics;
Muscular diseases;
Diagnosis;
Treatment;
Biological markers
- From:
Chinese Journal of Neurology
2019;52(6):441-445
- CountryChina
- Language:Chinese
-
Abstract:
Although myopathy has obvious heterogeneity in clinic,the exact mechanism of myopathy is not fully understood,and there is no effective biomarker,and there are one or some protein changes in the basic pathogenesis of myopathy.Proteomics is a discipline that explores the composition,expression and modification of proteins at a holistic level and is widely used in various fields of life sciences.The study of differential proteomics provides more scientific basis for explaining the pathogenesis of diseases,searching for new diagnostic markers and potential therapeutic targets.The application of proteomics in the study of muscular diseases deserves more attention from neurologists.