Application of Zebrafish Model in TCM Screening in Cardiovascular Diseases and Mechanism Research
10.3969/j.issn.1005-5304.2018.09.033
- VernacularTitle:斑马鱼模型在心血管疾病中药筛选和机制研究中的应用
- Author:
Hui ZHAO
1
;
Hua FAN
;
Duan ZHOU
;
You-Hua WANG
Author Information
1. 上海中医药大学附属龙华医院 上海 200032
- Keywords:
zebrafish;
cardiovascular;
TCM;
screening;
mechanism;
review
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2018;25(9):133-137
- CountryChina
- Language:Chinese
-
Abstract:
Zebrafish is one of the important model vertebrates in the study of life science at present. It has similar physiological and biochemical characteristics to mammals, and has the advantages of high efficiency, rapidness and largescale. TCM has complex active ingredients and various targets, so the application of zebrafish model in TCM research is increasingly wide. This article reviewed the application status of zebrafish model in TCM screening cardiovascular diseases and mechanism research from the aspects of angiogenesis, myocardial injury, hyperlipidemia, and cardiovascular toxicity.
