Effect of laparoscopic salpingotomy on ovarian reserve function in patients with tubal pregnancy
10.3760/cma.j.issn.1008?6315.2019.04.012
- VernacularTitle:腹腔镜下输卵管开窗取胚术对输卵管妊娠患者卵巢储备功能的影响
- Author:
Yuan ZHANG
1
;
Xie Beibe
Author Information
1. 冀中能源峰峰集团有限公司总医院妇产科
- Keywords:
Tubal pregnancy;
Laparoscopy;
Oviduct fenestration;
Salpingectomy;
Number of sinus follicles;
Ovarian volume
- From:
Clinical Medicine of China
2019;35(4):347-350
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of laparoscopic salpingotomy and salpingectomy on ovarian reserve function in patients with tubal pregnancy??Methods From October 2014 to March 2017,201 cases of tubal pregnancy in Jizhong energy Fengfeng Group Hospital were selected and divided into observation group (112 cases) and control group (89 cases) according to different treatment methods??The observation group was treated with laparoscopic salpingectomy, while the control group was treated with laparoscopic salpingectomy??The number of sinus follicles and ovarian volume were measured by color Doppler ultrasound at third days of menstruation on first,third,sixth months after the operation respectively and the ovulation was detected in 6 months after the operation??The intrauterine pregnancy of the two groups was observed one year after operation??Results There was no significant difference in the number and volume of healthy ovarian antral follicles between the two groups in 1,3 and 6 months after operation respectively (all P＞0??05)??The number of sinus follicles in the 1,3 and 6 months after the operation were (7??71 ± 3??12), (7??86 ± 2??03) and (7??65 ± 1??89) in observation group respectively,while that in the control group were (4??06 ± 1??05),(3??91 ± 1??14) and (4??89±2??03)respectively??There was no significant difference in the number of sinus follicles in different time groups ( Fintra?group＝0??573,P＞0??05)??The difference between the groups was statistically significant (F inter?grouP＝634??306,P＜0??01,Finteraction＝463??257,P＜0??01)??The ovarian volume of the patients in the 1,3 and 6 months after the operation were (8??49 ± 1??67),(9??01 ± 3??07) and ( 8??51 ± 2??67) cm3 in observation group respectively, and were ( 5??70 ± 2??58), ( 4??81 ± 2??10) and ( 6??03 ± 1??96) cm3 in control group respectively??There was no significant difference in the ovarian volume of the affected side at different time points after operation( Fintra?group＝0??671,P＞0??05)??The difference between the groups was statistically significant ( Finter?group＝ 449??106, P＜ 0??01 ), F interaction＝ 261??017, P＜ 0??01 )??The ovulation rate at 6 months ( 82??1%, 92／112 ) and intrauterine pregnancy rate at 1 year ( 71??8%,79／110) in the observation group were higher than those in the control group (56??2%,50／89) and (31??0%,27／87)??There were significant differences between the two groups(χ2＝12??601,28??753,all P＜0??05)??Conclusion Laparoscopic salpingotomy is better than salpingectomy in the treatment of tubal pregnancy??The ovulation rate and intrauterine pregnancy rate are also superior to salpingectomy??It shows that laparoscopic fenestration can protect the ovarian reserve reserve function and reproductive function of patients??
