Research progress in the diagnosis and treatment of persistent inflammation-immunosuppression catabolism syndrome in severe acute pancreatitis
10.3760/cma.j.issn.1673-9752.2019.07.016
- VernacularTitle:重症急性胰腺炎持续炎症-免疫抑制-分解代谢综合征的诊断与治疗研究进展
- Author:
Qi FANG
1
;
Jing TAO
;
Jian CHANG
Author Information
1. 武汉大学人民医院胰腺外科 430060
- Keywords:
Severe acute pancreatitis;
Persistent inflammation-immunosuppression catabolism syndrome;
Diagnosis;
Pathophysiology;
Therapy
- From:
Chinese Journal of Digestive Surgery
2019;18(7):701-704
- CountryChina
- Language:Chinese
-
Abstract:
Severe acute pancreatitis (SAP) has a severe attack and high incidence of case fatality rate.Almost all the SAP patients would undergo some different immune status including systemic inflammatory response syndrome,compensatory anti-inflammatory response syndrome and mixed antagonistic response syndrome.With more acknowledgement of the pathophysiology of SAP,come researches have revealed that a few SAP patients may gradually come into a terribly and durably consumptive phase,and ultimately progress to persistent inflammation-immunosuppression catabolism syndrome (PICS).Now the morbidity of PICS has increased in recent years,therefore,it is helpful to recognize PICS early and improve the prognosis by discussing the pathophysiology deeply.Based on the new research progress at home and abroad,this article reviewed the diagnostic criteria,occurrence and development,and treatent of PICS in SAP,in order to offer treatment strategy for the SAP.
