Research progress on the pathogenesis and treatment of Enterococcus faecalis in pulp periapical disease
- Author:
LI Yingxue
1
;
WANG Yufei
1
;
ZHANG Linglin
1
Author Information
- Publication Type:Review
- Keywords: Enterococcus faecalis; pulpal and periapical diseases; root canal infection; pathogenic mechanism; antimicrobial therapy
- From: Journal of Prevention and Treatment for Stomatological Diseases 2019;27(8):535-540
- CountryChina
- Language:Chinese
- Abstract: Enterococcus faecalis is an important pathogen in pulp periapical disease that has been widely studied in recent years. A large number of studies have shown that the high detection rate of Enterococcus faecalis in root canals with persistent or secondary infection after root canal therapy is closely related to the failure of root canal therapy. The presence of Enterococcus faecalis in periapical pulp disease is related to its pathogenicity and virulence factors. Enterococcus faecalis can directly invade host tissues or induce immune inflammation in host tissues, resulting in periapical pulp tissue damage and lesions. Enterococcus faecalis has a strong tolerance to conventional root canal antibiotics and disinfection methods and is difficult to completely remove from the complex root canal system. How to fight Enterococcus faecalis infection has become an important direction in the treatment of pulp periapical disease. This article reviews the pathogenic mechanism of Enterococcus faecalis infection in pulp periapical disease and the progress in its treatment.
- Full text:粪肠球菌在牙髓根尖周病中致病机制及抗菌治疗的研究进展.pdf
