Clinical research progress on ocular fundus changes occur in Alzheimer's disease
10.3760/cma.j.issn.1005-1015.2019.03.021
- VernacularTitle:阿尔茨海默病眼底改变相关临床研究进展
- Author:
Zebing LI
1
;
Xi SHEN
Author Information
1. 上海交通大学医学院附属瑞金医院眼科 200025
- Keywords:
Alzheimer's disease;
Retina/physiopathology;
Review
- From:
Chinese Journal of Ocular Fundus Diseases
2019;35(3):298-302
- CountryChina
- Language:Chinese
-
Abstract:
Alzheimer's disease is a common neuro-degenerative disease.The clinical diagnosis mainly depends on the patient's complaint,the score of mini-mental state examination and Montreal cognitive assessment scale,and the comprehensive judgment of MRI and other imaging examinations.Retina is homologous to brain tissue,and their vascular systems have similar physiological characteristics to small blood vessels in the brain.Numerous studies found that the thickness of retinal nerve fiber layer,visual function,retinal blood vessels and retinal oxygen saturation were changed in AD patients to different degrees.To explore the formation mechanism and significance of ocular fundus changes in AD patients will be helpful to select specific,sensitive and simple methods for early observation and evaluation of AD.
