Visualization of tumor microenvironment and PET molecular imaging
10.3760/cma.j.issn.2095-2848.2019.03.014
- VernacularTitle:PET分子影像与肿瘤微环境的可视化
- Author:
Hongyan LI
1
;
Xiaotian XIA
;
Xiaoli LAN
;
Yongxue ZHANG
Author Information
1. 华中科技大学同济医学院附属协和医院核医学科、分子影像湖北省重点实验室
- Keywords:
Tumor microenvironment;
Positron-emission tomography;
Trends
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2019;39(3):174-177
- CountryChina
- Language:Chinese
-
Abstract:
Tumor microenvironment is different from the microenvironment formed by normal cells and surrounding tissues.It is composed of tumor cells,stromal cells,extracellular matrix (ECM),vasculature and various cytokines.Tumor microenvironment can promote the genesis,development,metastasis and resistance to therapy of tumor.Using PET molecular imaging to show tumor microenvironment can provide important biological information for early precise diagnosis and treatment intervention,as well as therapeutic effect evaluation and prognosis of tumor.In this paper,the main application categories and prospects of PET molecular imaging in tumor microenvironment are reviewed.