Advance in Exercise and Related Mechanisms for Parkinson's Disease (review)
10.3969/j.issn.1006-9771.2018.00.010
- VernacularTitle:帕金森病运动训练方法及其机制的研究进展
- Author:
Ya-Hui LI
1
;
Xiao-Hong LI
Author Information
1. 大连医科大学
- Keywords:
Parkinson's disease;
rehabilitation;
neural plasticity;
neurotransmitters;
brain-derived neurotrophic factor;
review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2019;25(1):51-54
- CountryChina
- Language:Chinese
-
Abstract:
Parkinson's disease is a common degenerative disease of central nervous system. Exercise for Parkinson's disease includes Taiji Quan, treadmill, dance and balance training, etc. Taiji Quan exercise is mainly for balance function, and treadmill training for gait obstacles. Dance can improve not only balance and gait, but also cognition and emotion. The possible molecular mechanism may involve to adjust the content of dopaminergic neurons in the nigrostatin, increase the content of non-dopaminergic transmitters, increase brain-derived neurotrophic factors, promote the plasticity of nerve cells, reduce oxidative stress, enhance mitochondrial activity, and activate the immune system, etc., to slow the degeneration of dopaminergic neurons and improve the symptoms of Parkinson's disease.
