Clinical research progress of Hodgkin lymphoma
10.3760/cma.j.issn.1009-9921.2019.02.004
- VernacularTitle:霍奇金淋巴瘤临床研究进展
- Author:
Jing ZHANG
1
;
Lei FAN
;
Jianyong LI
Author Information
1. 南京医科大学第一附属医院 江苏省人民医院血液科 210029
- Keywords:
Hodgkin lymphoma;
Treatment;
Prognosis
- From:
Journal of Leukemia & Lymphoma
2019;28(2):75-78
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, research on Hodgkin lymphoma (HL) has made great progress. In basic research field, whole exon sequencing and other assay suggest that HL uses multiple genetic mechanisms to escape immune monitoring. In staging and prognosis aspects, PET-CT guided staging and prognostic indicators, as well as some biological indicators may help to stratify patients more exactly; treatment progress includes options of early chemotherapy and radiotherapy, along with efficacy and safety studies of checkpoint blockade, novel treatment regimens as well as updated data of clinical trials. The progress of HL reported in the 60th American Society of Hematology (ASH) Annual Meeting is introduced in this paper.