Complications Following Colonoscopy in a Nationwide Standard Cohort: A Retrospective Case-control Study
10.4166/kjg.2019.73.3.152
- Author:
Ji Woo KIM
1
;
Su Young KIM
;
Jung Hye CHOI
;
Hyun Soo KIM
;
Jung Kuk LEE
;
Yun Tae KIM
;
Geunu PARK
;
Dae Ryong KANG
Author Information
1. Department of Medicine, Yonsei University Wonju College of Medicine Wonju, Korea.
- Publication Type:Original Article
- Keywords:
Colonoscopy;
Complications;
Intestinal perforation
- MeSH:
Case-Control Studies;
Cohort Studies;
Colonoscopy;
Humans;
Incidence;
Intestinal Perforation;
Korea;
Male;
Methods;
National Health Programs;
Retrospective Studies
- From:The Korean Journal of Gastroenterology
2019;73(3):152-158
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: Despite the many reports of colonoscopy complications worldwide, few studies have been performed at the population level in Korea. In this study, a population-based study was performed to evaluate the incidence of post-colonoscopy perforations compared to a control group. METHODS: Between January 2011 and December 2011, data for all cases (age over 45) who underwent a colonoscopy were collected from National Health Insurance Service using a random sampling method. The clinical characteristics and perforation incidence (within 30 days after the colonoscopy) of cases were identified, and cases were then compared with controls who had not undergone a colonoscopy. RESULTS: Among 1,380,000 subjects, 31,177 cases and 62,354 controls were identified. Perforation occurred in 14 patients (0.04%) in the case group and one patient (<0.01%) in the control group (RR, 28.0; 95% CI 3.7–212.9, p<0.001). Subgroup analysis was followed according to the endoscopic procedure, gender and age. In subgroup analysis, colonoscopy-associated perforations occurred more in the therapeutic procedure (RR, 26; 95% CI 1.46–461.46), male (RR, 50; 95% CI 2.96–844.41), and age of 45–60 years (RR, 30; 95% CI 1.71–525.23). CONCLUSIONS: A colonoscopy procedure is related to an increased risk of perforation at the population level. In addition, the therapeutic procedure, male, and age of 45-60 years appeared to be associated with an increased risk of perforation.
