Java Ginger Bangle

VernacularTitle:ジャワしょうがバングレ
Author: Nobutaka SUZUKI ¹ ; Hoko KYO ¹ ; Kazuo UEBABA ²
Author Information

1. Department of Complementary and Alternative Medicine Clinical Research and Development, Kanazawa University Graduate School of Medical Science
2. Teikyo Heisei University
Keywords: Java ginger bangle; neurotrophin-mimic active compound; banglene; dementia; MCI (Mild Cognitive Impairment); MoCA-J
From:Japanese Journal of Complementary and Alternative Medicine 2019;16(1):1-6
CountryJapan
Language:Japanese
Abstract: The review reveals latest studies of Bangle that has unique ingredients, safety, healthy effect and especially neurotrophin activity. Banglenes have some neurotrophin activity such as neuritogenesis without NGF in vitro, property that enhances hippocampal neurogenesis and crosses the blood-brain barrier (BBB) in vivo. On the other hand, Java ginger bangle (Extract) improves spatial learning in Senescence-Accelerated Mouse. Moreover the human clinical trial for MCI (Mild Cognitive Impairment) have been just started.