Analysis of the efficacy of superselective intravascular embolization in the treatment of large hemangioma in children
10.3760/cma.j.issn.1005-1201.2018.12.014
- VernacularTitle:超选择血管内栓塞治疗儿童大型血管瘤的疗效影响因素分析
- Author:
Xinxian LIU
1
;
Qiang LIU
;
Sui HUANG
;
Fan LIU
;
Yu CHEN
Author Information
1. 430016,华中科技大学同济医学院附属武汉儿童医院(武汉市妇幼保健院)影像中心
- Keywords:
Chemoembolization,therapeutic;
Hemangioma;
Treatment outcome;
Prognosis
- From:
Chinese Journal of Radiology
2018;52(12):952-956
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical efficacy of superselective intravascular embolization in the treatment of large hemangiomas in children,and to provide a reliable basis for the clinical treatment and to predict prognosis.Methods The clinical and imaging data of 85 children with large hemangiomas who underwent superselective angiography and embolization were collected in our hospital from January 2015 to January 2018,and followed up for 3 months to 1.5 years.According to the DSA angiography of the hemangioma [artery origin,artery number,arterio-venous fistula(AVF)],and combined with age,tumor size and the selection and compatibility of embolization materials.Using the chi-square test to analyze these indicators.Results Analysis of the clinical efficacy indicators,was shown as the following:(1) Artery origin:The total effectiveness rate of single and mixed sources was 95.3％ (61/64),66.7％ (14/21) respectively.The difference was statistically significant (x2=0.688,P＜0.05).(2) Feeding artery number:The total effectiveness rate of 1 branch,2 branches and ≥3 branches was (3/3),(25/27)and (47/55) respectively.The difference was statistically significant (x2=1.944,P＜0.05).(3) Presence of fistula(AVF):The total effectiveness rate of AVF and without AVF was 36.4％ (4/11) and (95.9％,71/74) respectively.The difference was statistically significant (x2=0.806,P＜0.05).Other influencing factors including:(1)Age:the recurrence rate of patients≤5 months and＞5 months was 33.3％ (6/18) and 20.9％ (14/67)respectively.There was no significant difference (x2=1.220,P＞0.05);(2)Tumor size:The recurrence rate of φ≤80 mm and φ＞80 mm was 25.5％(13/51)and 32.4％(11/34) respectively.There was no significant difference (x2=0.474,P＞0.05).(3) Selection and compatibility of embolization materials:The recurrence rate of Lipiodol + bleomycin and gelatin sponge +bleomycin was 27.0％ (10/37) and 31.3％ (15/48) respectively.There was no significant difference (x2=0.179,P＞0.05).Conclusions The clinical efficacy of superselective intravascular embolization in the treatment of large hemangioma in children was influenced by:artery origin(mixed sources),artery number (≥3 branches),AVF,age tumor size,selection and compatibility of embolic materials.
