Therapeutic effect and safety of oral musk Baoxin pill in patients with stable angina pectoris of coro-nary heart disease
10.3969/j.issn.1008-0074.2018.06.17
- VernacularTitle:冠心病稳定型心绞痛患者口服麝香保心丸的疗效及安全性分析
- Author:
Hong-Mei LIU
1
Author Information
1. 陕西省宝鸡市人民医院内二科
- Keywords:
Coronary disease;
Angina,Stable;
Shexiang Baoxin pill
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2018;27(6):684-687
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore therapeutic effect and safety of oral musk Baoxin pill in patients with stable angina pectoris (SAP) of coronary heart disease (CHD).Methods:A total of 158 SAP patients of CHD treated in our hos-pital were selected,and were randomly divided into routine treatment group (n=79) and musk Baoxin pill group (n=79,received musk Baoxin pill based on routine treatment ),both groups were treated for eight weeks.Therapeutic effect and safety were compared between two groups.Results:After treatment,there was no significant difference in total effective rate of ECG improvement between two groups,P=0.475.Compared with routine treatment group after treatment,there were significant reductions in onset times of angina pectoris [(1.68 ± 0.43) times/d vs.(1.12 ± 0.37) times/d] and nitroglycerin consumption [(1.65 ± 0.87)/d vs.(1.08 ± 0.47)/d],and significant rise in to-tal effective rate of angina pectoris improvement (81.01% vs.96.20%) in musk Baoxin pill group,P=0.001 all.No obvious adverse reactions occurred in two groups.Conclusion:Oral musk Baoxin pill based on routine treatment can significantly relieve angina pectoris symptoms and the safety is good in patients with stable angina pectoris of coronary heart disease.