Anti-myelin oligodendrocyte glycoprotein antibody and central nervous system immune demyelinating diseases
10.3760/cma.j.issn.2095-428X.2018.24.021
- VernacularTitle:抗髓鞘少突胶质细胞糖蛋白抗体与中枢神经系统免疫性脱髓鞘
- Author:
Ji ZHOU
1
;
Ye WU
Author Information
1. 100034,北京大学第一医院儿科
- Keywords:
Anti-Myelin oligodendrocyte glycoprotein antibody;
Neuromyelitis optica spectrum disease;
Acute disseminated encephalomyelitis
- From:
Chinese Journal of Applied Clinical Pediatrics
2018;33(24):1918-1920
- CountryChina
- Language:Chinese
-
Abstract:
Myelin oligodendrocyte glycoprotein (MOG) is a component of central nervous system myelin.Anti-MOG antibodies are important in both pediatric and adult demyelination and the clinical association of MOG antibody-induced demyelination has been refined to include neuromyelitis optica spectrum disease,optic neuritis,and acute disseminated encephalomyelitis.But there are still many questions about epidemiological,clinical,radiological,and prognostic profile in patients with MOG antibody-associated demyelination.No consensus has been reached on detecting this antibody.This review will summarize the advances in anti-Myelin oligodendrocyte glycoprotein antibody.
