Analysis of operation feasibility in ventricular septal defects and congestive heart failure newborns
10.3760/cma.j.issn.2095-428X.2013.18.020
- VernacularTitle:室间隔缺损并充血性心力衰竭新生儿手术可行性分析
- Author:
Xiao-Yang HONG
1
;
Geng-Xu ZHOU
;
Xuan XU
;
Yu-Hang LIU
;
Hui WANG
;
Ying-Yue LIU
;
Zhi-Chun FENG
Author Information
1. 100007 北京军区总医院附属八一儿童医院PICU;南方医科大学八一临床医学院附属八一儿童医院PICU
- Keywords:
Ventricular septal defect;
Congestive heart failure;
Cardiopulmonary bypass;
Newborn infant
- From:
Chinese Journal of Applied Clinical Pediatrics
2013;28(18):1430-1432
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the feasibility and safety on closing ventricular septal defects (VSDs) under cardiopulmonary bypass(CPB) in neonatal patients with VSD and congestive heart failure.Methods From Oct.2010 to Sep.2012,16 newborn infants with VSD and congestive heart failure in Neonatal Intensive Care Unit(NICU),the Bayi Children's Hospital Affiliated to Beijing Military General Hospital,were selected as the observed group,VSD repair operation was done under CPB.As the control group,18 patients in Pediatrical Cardiac Surgical Department were randomly selected in the same period in hospital,and selective VSD repair operations were done under CPB.Between the 2 groups,demographics(body weight,gender,VSD diameter),clinical characteristics (CPB time,aortic crossclamp time) and early outcomes were compared.Results For the diameter of VSD and gender,there were no significant difference between the 2 groups (P ＞ 0.05).For the body weight,the patients in control group [(8.27 ± 3.39) kg] were more heavier than those in observed group [(3.69 ± 0.72) kg] (P ＜ 0.01).In the operation period,there were no significant differences in CPB time and aortic crossclamp time between 2 groups(all P ＞ 0.05).The lactate value of the patients in observed group [(2.76 ± 1.12) mmol/L] was significantly higher than that in control group [(1.65 ±0.34) mmol/L] (P ＜ 0.01).At the same time,the ventilation time [(3.69 ± 1.66) days] and PICU stay [(9.75 ± 3.44) days] were significantly longer than those in control group[(2.00 ±0.89) days and (6.17 ± 1.98) days] (all P ＜ 0.01).All the patients in the 2 groups discharge out of the hospital,there was no significant difference in outcome.Conclusions The newborns with VSD and congestive heart failure in NICU,can be not improved after the medical management,then closing the VSD is feasible and safe under CPB.
