Clinical use of biomarkers in pediatric heart failure
10.3760/cma.j.issn.2095-428X.2013.07.019
- VernacularTitle:生物标志物在儿童心力衰竭中的临床应用
- Author:
Wen-Shu WANG
1
;
Jie TIAN
Author Information
1. 400014,重庆医科大学附属儿童医院心内科
- Keywords:
Biological marker;
Heart failure;
Child
- From:
Chinese Journal of Applied Clinical Pediatrics
2013;28(7):546-548
- CountryChina
- Language:Chinese
-
Abstract:
Heart failure includes many biological courses,such as neurohormonal,inflammation,oxid-ative stress,extracellular matrix remodeling,myocyte injury,myocyte stress,et al.All of these courses have their specific biomarkers,which can be used to estimate the process of heart failure.It is difficult to estimate pediatric heart failure severity and stage objectively just with medical histories,symptoms and signs.So these clinical characteristics needed to link up with the biomarkers.At present,biomarkers are getting into more extensive use in heart failure,including early diagnosis,differential diagnosis,risk stratification,therapy guiding,prognostic indication and calculation of targeted therapeutic strategies,et al.This review puts emphasis on the clinical use of some important biomarkers in pediatric heart failure.
