Diagnosis and Glycemic Control of Type 1 Diabetes.
10.4093/jkd.2015.16.2.101
- Author:
Jae Hyun KIM
1
Author Information
1. Department of Pediatrics, Inje University Ilsan Paik Hospital, Goyang, Korea. pedendo@paik.ac.kr
- Publication Type:Original Article
- Keywords:
Diagnosis;
Glycemic target;
Type 1 diabetes
- MeSH:
Adult;
Autoantibodies;
Blood Glucose;
C-Peptide;
Diabetes Mellitus, Type 1;
Diagnosis*;
Education;
Fasting;
Glucose;
Glucose Tolerance Test;
Humans;
Incidence;
Insulin;
Life Style
- From:Journal of Korean Diabetes
2015;16(2):101-107
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Type 1 diabetes mellitus (T1DM) is characterized by an immune-mediated beta-cell destruction that causes lifelong insulin dependency. Diagnosis of diabetes is based on fasting glucose, 2-h plasma glucose value after a 75-g oral glucose tolerance test, or hemoglobin A1c (HbA1c) levels. Differentiation between type 1 and 2 diabetes is important for both education and treatment. Diabetes-associated autoantibodies, c-peptide and clinical characteristics should be considered to confirm the diagnosis of T1DM. A single HbA1c target of < 7.5% across all pediatric age groups is recommended. In nonpregnant adults, a reasonable HbA1c goal is < 7.0% to reduce the incidence of microvascular complications of T1DM. Glycemic targets should be individualized according to lifestyle, psychosocial and medical circumstances.
