A Correlation of Cognitive Function, Depression, Suicidal Idea and Serum Lipid Levels in the Elderly Over Sixty Years of Age.
- Author:
Jung Joon MOON
1
;
Bong Ju LEE
;
Jeong Eun KIM
;
Woo Jin KIM
;
Min Hyo KIM
;
Min Kyong PARK
;
Tae Hong SONG
;
Joo Cheol SHIM
;
Gyung Mee KIM
;
Jung Goo LEE
;
Young Hoon KIM
Author Information
1. Department of Psychiatry, Inje University College of Medicine, Busan, Korea. npkyh@chol.com
- Publication Type:Original Article
- Keywords:
Cognitive function;
Geriatric depression;
Suicidal ideation;
Serum lipid level
- MeSH:
Aged;
Cholesterol, HDL;
Cholesterol, LDL;
Depression;
Humans;
Prevalence;
Risk Factors;
Suicidal Ideation
- From:Journal of the Korean Society of Biological Psychiatry
2010;17(4):210-217
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVES: We investigated a correlation of cognitive function, depression, suicidal idea and serum lipid levels in Korean elderly over 60 years old to find risk factors of deprssion and cognitive decline. METHODS: 834 persons participated in this study. Clinical evaluation was done at a point by using Mini-Mental State Examination in the Korean version of CERAD assessment packet(MMSE-KC). We also evaluated 165 persons that agreed to our exact examination for Geriatric Depression Scale(GDS), Scale for Suicidal Ideation(SSI), Hachinski Ischemic Score and serum lipid profile. Correlation analysis was used to evaluate correlation among serum lipid levels, MMSE-KC and SSI. One-way ANOVA was used for comparison of serum lipid levels and cognitive function, depression and SSI. We did a post-hoc analysis. RESULTS: Depression and suicidal ideation were related with cognitive impairment in Korean elderly over 60 years old. Those who have more severe cognitive impairment and depressive symptom, have higher Hachinski ischemic score. We can see high HDL cholesterol levels only in the normal control group. Low total, HDL, LDL cholesterol were related with depression. CONCLUSION: There was high prevalence of depression in the Korean elderly over 60 years old and low serum lipid level was related with severity of depression and high suicidal ideation. In the normal control group, we can see high HDL cholesterol levels. To confirm this result, we need well-designed and wide range study.
