A Case of Relapsed Multiple Myeloma Presented as lntracranial Extramedullary Plasmacytoma.
- Author:
Dong Woo HYUN
1
;
Jin Ho BAIK
;
Dong Hwan KIM
;
Jin Tae JUNG
;
Sang Kyun SOHN
;
Jae Tae LEE
;
Kyu Bo LEE
Author Information
1. Department of Internal Medicine, Kyungpook National University, School of Medicine, Taegu, Korea.
- Publication Type:Case Report
- Keywords:
Multiple myeloma;
Intracranial extramedullary plasmacytoma
- MeSH:
Biopsy;
Brain;
Cavernous Sinus;
Cranial Nerve Diseases;
Drug Therapy;
Electrophoresis;
Headache;
Humans;
Multiple Myeloma*;
Optic Chiasm;
Paralysis;
Pituitary Gland;
Plasmacytoma*;
Radiotherapy;
Vertigo
- From:Korean Journal of Hematology
1998;33(3):460-465
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Intracranial plasmacytoma presented by extramedullary involvement of multiple myeloma is rarely reported. Neurologic complications by intracranial extramedullary plasmacytomas are cranial nerve palsy, visual disturbance, vertigo, nystagmus, headache, paralysis, mental change and etc. We experienced a case of relapsed multiple myeloma presented as intracranial extramedullary plasmacytoma. Brain magnetic resonance imaging(MRI) disclosed a large soft tissue mass involving the sphenoidal sinus and cavernous sinus which invaded optic chiasma, occulomotor nerve and pituitary gland. Relapsed multiple myeloma with intracranial extramedullary plasmacytoma was confined by trans-sphenoidal biopsy and urine electrophoresis. Neurologic complications of the patient was improved after cranial radiotherapy and systemic chemotherapy.
