A Case of an Untreated Acute Myeloid Leukemia Patient with Invasive Aspergillosis that Developed at the Colon.
10.5045/kjh.2006.41.2.115
- Author:
Ji Yoon MOON
1
;
Young Jin CHOI
;
Ho Jin SHIN
;
Joo Seop CHUNG
;
Moo Kon SONG
;
Dong Cheul HAN
;
Ji Young PARK
;
Kyung Yup KIM
;
Hwal Woong KIM
;
Goon Jae CHO
Author Information
1. Department of Internal Medicine, Pusan National University College of Medicine, Busan, Korea. hojinja@daum.net
- Publication Type:Case Report
- Keywords:
Aspergillosis;
Leukemia;
Gastrointestinal tract
- MeSH:
Abdominal Pain;
Adrenal Glands;
Amphotericin B;
Aspergillosis*;
Biopsy;
Cecum;
Central Nervous System;
Colon*;
Colonoscopy;
Diarrhea;
Drug Therapy;
Gastrointestinal Tract;
Humans;
Leukemia;
Leukemia, Myeloid, Acute*;
Liver;
Lung;
Spleen;
Stem Cell Transplantation;
Ulcer
- From:Korean Journal of Hematology
2006;41(2):115-118
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Invasive aspergillosis needs to be paid extra attention to these day since chemotherapy and stem cell transplantation bring about immune suppression. The lung is the main portal of entry and once involved, invasive aspergillosis may be delivered by hematogenous spread into the central nervous system, liver, spleen, gut and adrenal gland. However infections through the gastrointestinal track are not common. In these cases, abdominal pain and diarrhea can be the major symptoms and amphotericin B is the treatment of choice. We report here on a patient with untreated acute myeloid leukemia who suffered from bloody diarrhea without any lung lesion; this patient had ulcer close to cecum on colonoscopy, and then he was diagnosed as suffering with aspergillosis with H&E staining and PAS staining on the biopsy specimen.
