Midterm Follow-up after Cryopreserved Homograft Replacement in the Aortic Position.
- Author:
Samina PARK
1
;
Ho Young HWANG
;
Kyung Hwan KIM
;
Ki Bong KIM
;
Hyuk AHN
Author Information
1. Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Korea. ahnhyuk@snu.ac.kr
- Publication Type:Original Article
- Keywords:
Homograft;
Endocarditis;
Aortic root;
Aorta
- MeSH:
Acute Kidney Injury;
Aorta;
Arrhythmias, Cardiac;
Cardiac Output, Low;
Endocarditis;
Follow-Up Studies;
Humans;
Survival Rate;
Systemic Vasculitis;
Transplantation, Homologous;
Transplants
- From:The Korean Journal of Thoracic and Cardiovascular Surgery
2012;45(1):30-34
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: The long-term results of homografts used in systemic circulation are controversial. We assessed the long-term results of using a cryopreserved homograft for an aortic root or aorta and its branch replacement. MATERIALS AND METHODS: From June 1995 to January 2010, 23 patients (male:female=15:8, 45.4+/-15.6 years) underwent a homograft replacement in the aortic position. The surgical techniques used were aortic root replacement in 15 patients and aortic graft interposition in 8 patients. Indications for the use of a homograft were systemic vasculitis (n=15) and complicated infection (n=8). The duration of clinical follow-up was 65+/-58 months. RESULTS: Early mortality occurred in 2 patients (8.7%). Perioperative complications included atrial arrhythmia (n=3), acute renal failure (n=3), and low cardiac output syndrome (n=2). Late mortality occurred in 6 patients (26.1%). The overall survival rates at 5 and 10 years were 66.3% and 59.6%, respectively. Six patients (28.6%) suffered from homograft-related complications. CONCLUSION: Early results of homograft replacement in aortic position were favorable. However, close long-term follow-up is required due to the high rate of homograft-related events.
