Bacterial infection monitoring in the early period after liver transplantation.
10.4174/astr.2018.94.3.154
- Author:
Ji Soo LEE
1
;
Seung Hwan LEE
;
Kyeong Sik KIM
;
Eun Mi GIL
;
Gyu Seoung CHOI
;
Jong Man KIM
;
Kyong Ran PECK
;
Choon Hyuck David KWON
;
Jae Won JOH
;
Suk Koo LEE
Author Information
1. Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. yjongman21@gmail.com
- Publication Type:Original Article
- Keywords:
Culture techniques;
Infection;
Liver transplantation
- MeSH:
Adult;
Ascites;
Bacterial Infections*;
Classification;
Culture Techniques;
Humans;
Immunosuppression;
Liver Diseases;
Liver Transplantation*;
Liver*;
Living Donors;
Masks;
Mortality;
Sputum;
Tissue Donors
- From:Annals of Surgical Treatment and Research
2018;94(3):154-158
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: Infection remains the main cause of morbidity and mortality in liver transplantation (LT) recipients; however infection is notoriously difficult to diagnose because its usual signs and symptoms of infection may be masked or absent. This study comprises an analysis of bacterial infections in the early period after LT. METHODS: This is a study of 129 adults who underwent LT from January 2013 to December 2013, and it includes patients who were followed daily from the day of transplantation to 1-week posttransplantation using bacteriological cultures of blood, urine, sputum, and drained ascites. RESULTS: The following factors were significantly different between the positive and negative culture groups: living donor LT vs. deceased donor LT (odds ratio [OR], 3.269; P = 0.003), model for end-stage liver disease score (OR, 4.364; P < 0.001), and Child-Pugh classification (P = 0.007). Neither positive culture nor negative culture was associated with infection within 4 weeks of surgery (P = 0.03), and most events were due to surgical complications (75%). CONCLUSION: Since the full effect of immunosuppression is not yet present during the first month after LT, we suggest that the number of bacterial culture test could be reduced such that they are performed every other day depending on patient's situation.
