Quality Metrics of a Fecal Immunochemical Test-Based Colorectal Cancer Screening Program in Korea.
- Author:
Dae Ho KIM
1
;
Jae Myung CHA
;
Min Seob KWAK
;
Jin Young YOON
;
Young Hak CHO
;
Jung Won JEON
;
Hyun Phil SHIN
;
Kwang Ro JOO
;
Joung Il LEE
Author Information
- Publication Type:Original Article
- Keywords: Colonoscopy; Colorectal neoplasms; Fecal occult blood test; Quality; Screening
- MeSH: Adenoma; Colonoscopy; Colorectal Neoplasms*; Europe; Humans; Korea*; Male; Mass Screening*; United States
- From:Gut and Liver 2018;12(2):183-189
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND/AIMS: Knowledge regarding the quality metrics of fecal immunochemical test (FIT)-based colorectal cancer screening programs is limited. The aim of this study was to investigate the performance and quality metrics of a FIT-based screening program. METHODS: In our screening program, asymptomatic subjects aged ≥50 years underwent an annual FIT, and subjects with positive FIT results underwent a subsequent colonoscopy. The performance of the FIT and colonoscopy was analyzed in individuals with a positive FIT who completed the program between 2009 and 2015 at a university hospital. RESULTS: Among the 51,439 screened participants, 75.1% completed the FIT. The positive rate was 1.1%, and the colonoscopy completion rate in these patients was 68.6%. The positive predictive values of cancer and advanced neoplasia were 5.5% and 19.1%, respectively. The adenoma detection rate in the patients who underwent colonoscopy after a positive FIT was 48.2% (60.0% for men and 33.6% for women). The group with the highest tertile quantitative FIT level showed a significantly higher detection rate of advanced neoplasia than the group with the lowest tertile (odds ratio, 2.6; 95% confidence interval, 1.4 to 5.1; p < 0.001). CONCLUSIONS: The quality metrics used in the United States and Europe may be directly introduced to other countries, including Korea. However, the optimal quality metrics should be established in each country.
