A Comparison of Ultrasound-Guided Fine Needle Aspiration versus Core Needle Biopsy for Thyroid Nodules: Pain, Tolerability, and Complications.
10.3803/EnM.2018.33.1.114
- Author:
Eun Ji JEONG
1
;
Sae Rom CHUNG
;
Jung Hwan BAEK
;
Young Jun CHOI
;
Jae Kyun KIM
;
Jeong Hyun LEE
Author Information
1. Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. radbaek@naver.com
- Publication Type:Original Article
- Keywords:
Thyroid nodule;
Biopsy, fine-needle;
Biopsy, large-core needle;
Safety
- MeSH:
Biopsy;
Biopsy, Fine-Needle*;
Biopsy, Large-Core Needle*;
Humans;
Needles;
Thyroid Gland*;
Thyroid Nodule*;
Visual Analog Scale
- From:Endocrinology and Metabolism
2018;33(1):114-120
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: To compare pain, tolerability, and complications associated with fine needle aspiration (FNA) versus core needle biopsy (CNB). METHODS: FNAs were performed using 23-gauge needles and CNBs were performed using 18-gauge double-action spring-activated needles in 100 patients for each procedure. Patients were asked to record a pain score using a 10-cm visual analog scale and procedure tolerability. Complications and number of biopsies were recorded. RESULTS: The median pain scores were similar for the FNA and CNB approaches during and 20 minutes after the biopsy procedures (3.7 vs. 3.6, P=0.454; 0.9 vs. 1.1, P=0.296, respectively). The procedure was tolerable in all 100 FNA patients and in 97 CNB patients (P=0.246). The mean number of biopsies was fewer in the CNB group (1.4 vs. 1.2, P=0.002). By subgroup analysis (staff vs. non-staff), no significant difference was detected in any parameter. There were no major complications in either group, but three patients who underwent CNB had minor complications (P=0.246). CONCLUSION: FNA and CNB show no significant differences for diagnosing thyroid nodules in terms of pain, tolerability, or complications.
