Emerging of Explosive Speech after Olanzapine in Multiple System Atrophy Patient.
10.12779/dnd.2018.17.1.37
- Author:
Yong Sung KIM
1
;
Seung Jae KIM
;
Jongmin LEE
;
Hee Jin KIM
Author Information
1. Department of Neurology, College of Medicine, Hanyang University, Seoul, Korea. hyumcbrain@hanyang.ac.kr
- Publication Type:Case Report
- Keywords:
Antipsychotic Agents;
Multiple System Atrophy;
Speech
- MeSH:
Antipsychotic Agents;
Cerebellar Ataxia;
Cerebellum;
Humans;
Multiple System Atrophy*;
Neurodegenerative Diseases;
Parkinsonian Disorders
- From:Dementia and Neurocognitive Disorders
2018;17(1):37-40
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: Cerebellum has an important role in sensorimotor control including speech. Multiple system atrophy (MSA) is a sporadic and rapidly progressive neurodegenerative disorder that presents with autonomic failure in combination with Parkinsonism or cerebellar ataxia. CASE REPORT: We report a case of MSA-cerebellum subtype associated with emergence of irreversible explosive speech following olanzapine therapy. CONCLUSIONS: Further investigation into speech problems in MSA according to subtype and disease severity is needed, and side effects of olanzapine therapy should also be considered.
