Research progress on the relationship between IgE and autoimmune diseases
10.3760/cma.j.issn.1009-9158.2018.03.013
- VernacularTitle:IgE与自身免疫性疾病关系的研究进展
- Author:
Yue YIN
1
;
Li LI
Author Information
1. 200080,上海交通大学附属第一人民医院检验科
- Keywords:
IgE;
IgE autoantibodies;
Autoimmune disease
- From:
Chinese Journal of Laboratory Medicine
2018;41(3):242-245
- CountryChina
- Language:Chinese
-
Abstract:
IgE is closely related to autoimmune diseases.On the one hand,a variety of autoimmune diseases found the increasing IgE.This IgE is just as allergen-specific IgE or IgE autoantibody is not yet clear.On the other hand, the pathogenic mechanism of IgE includes not only the direct damage due to immune complex deposition,activation of basophils and mast cells releasing inflammatory mediators,but also includes the autoimmune effects of type I interferons produced by plasma cell -like dendritic cells.This article expounds the relationship between IgE and the occurrence and development of several autoimmune diseases.
