Vasoactive-inotropic score as a predictor of outcome in children after cardiac surgery with bypass
10.3760/cma.j.issn.1001-4497.2018.03.003
- VernacularTitle:先天性心脏病术后患儿血管活性药物评分与其预后关系
- Author:
Jie REN
1
;
Xiaoyu XIONG
;
Chengjun LIU
;
Feng XU
;
Fang ZHOU
;
Jing LI
Author Information
1. 400014,重庆医科大学附属儿童医院重症医学科 儿童发育疾病研究教育部重点实验室儿童发育重大疾病国家国际科技合作基地 儿科学重庆市重点实验室
- Keywords:
Congenital heart disease;
Vasoactive-inotropic score;
Outcome
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2018;34(3):139-143
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the vasoactive-inotropic score(VIS) as a predictor of outcome in children following surgery for congenital heart disease.Methods A retrospective chart review of 472 children undergoing cardiac surgery with bypass.VIS values were calculated during the first 72 postoperative hours,and the maximum and mean scores in the first,second and third 24 postoperative hours [VIS (24max),VIS (24mean),VIS (48max),VIS (48mean),VIS (72max),VIS (72mean)] were also recorded.Chi-test,t-test,and ROC curves were performed for the association between VIS and the clinical outcomes.Results ROC analysis indicated the VIS (24max) was strongly associated with poor outcomes (AUROC =0.919,P =0.000).And the high V IS (24max) defi ned as 19.5 and above,which may lead poor outcomes (J =0.70).When the interplay between a range of factors was controlled,only lactate and VIS(24max) was related to the prognosis.Conclusion Maximum VIS calculated in the first 24 hours[VIS(24max)] after PICU admission was strongly and significantly associated with clinical outcomes in children after cardiac surgery.The greater the VIS,the worse the illness,the poorer the outcome,the higher the mortality.
