Advances in placental glucose transport in hyperglycemic pregnant women
10.3760/cma.j.issn.1007-9408.2018.10.009
- VernacularTitle:妊娠期高血糖胎盘葡萄糖转运代谢的研究进展
- Author:
Wanyi ZHANG
1
;
Huixia YANG
Author Information
1. 100034 北京大学第一医院妇产科;妊娠合并糖尿病母胎医学北京市重点实验室
- Keywords:
Hyperglycemia;
Pregnancy complications;
Glucose transport proteins,facilitation
- From:
Chinese Journal of Perinatal Medicine
2018;21(10):687-690
- CountryChina
- Language:Chinese
-
Abstract:
As a common pregnancy complication,hyperglycemia in pregnancy has an important impact on pregnancy outcomes and the short-and long-term health of both mothers and babies.Placenta is important for maternal-fetal transport of nutrients and its capability of glucose transportation,which is influenced by the expression and regulation of glucose transporters,is crucial for hyperglycemia in pregnancy women.In this review,we summarized research results on the distribution and expression of several common placental glucose transporters in women with different types of hyperglycemia in pregnancy and their association with offspring development,as well as the main regulatory mechanisms affecting the expression of glucose transporters in order to provide evidences for understanding the mechanism of the effect of hyperglycemia in pregnancy on maternal and fetal health.
