Postoperative analgesic effect of parecoxib in combination with incision infiltration by local anesthetics after laparoscopic inguinal hernia repair
10.3760/cma.j.issn.1007-631X.2018.06.018
- VernacularTitle:帕瑞昔布结合切口局麻用于腹腔镜腹股沟疝修补术后镇痛的临床研究
- Author:
Jianxin CHEN
1
;
Ruiping LI
;
Libo LI
Author Information
1. 东莞市南方医科大学附属东莞市人民医院普通外科二区
- Keywords:
Hernia,inguinal;
Anesthesia,local;
Laparoscopes;
Parecoxib
- From:
Chinese Journal of General Surgery
2018;33(6):505-507
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the postoperative analgesic effect of parecoxib following laparoscopic inguinal hernia repair when local anesthetics was infiltrated at incision site.Methods 160 patients were divided into four groups (40 in each group).Group A received intravenous 4 ml saline and incision infiltration with saline in ten minutes before thc end of operation.Group B received intravenous parecoxib 40 mg and incision infiltration with saline.Group C received intravenous 4 ml saline and incision infiltration with 0.75％ ropivacaine.Group D received intravenous parecoxib 40 mg and incision infiltration with 0.75％ ropivacaine.Results There was no significant difference between group A and group C of the VAS scores at 6 hours,while the VAS values in group D was significantly lower than group A,B and C (P ＜ 0.05).There was no significant difference among group A,B and C in VAS at 24 hours (P ＞ 0.05),while VAS in group D was significantly lower than others (P ＜ 0.05).The satisfactory rate with analgesia in group D (95％) was significantly higher than other three groups (P ＜ 0.05).Conclusions Paricoxib combined with local anesthetics infiltration can significantly relieve the pain at postoperative early stage in patients receiving laparoscopic inguinal hernia repair.
