Study on the correlation between normal serum TSH level and components of metabolic syndrome in Guiyang urban residents aged 40-80 years
10.3760/cma.j.issn.1000-6699.2018.01.007
- VernacularTitle:贵阳市城区40～80岁居民正常血清TSH水平与代谢综合征及其组分的相关性研究
- Author:
Yang YANG
1
;
Lixin SHI
;
Qiao ZHANG
;
Nianchun PENG
;
Ying HU
Author Information
1. 贵州医科大学附属医院内分泌代谢病科
- Keywords:
Metabolic syndrome;
TSH;
Insulin resistance
- From:
Chinese Journal of Endocrinology and Metabolism
2018;34(1):34-37
- CountryChina
- Language:Chinese
-
Abstract:
A total of 10140 adult residents aged 40-80 years living for more than five years in Yunyan district of Guiyang were recruited by cluster sampling method from May to October, 2011. The epidemiological questionnaire investigations were performed in all subjects and basic information was collected. Body mass index (BMI), waist circumference, blood pressure, blood glucose, blood lipids, serum insulin, and TSH levels were measured. The results showed that the prevalence of metabolic syndrome ( MS) was 40. 3％ in 7743 subjects with normal thyroid function, which was 27. 4％ for men and 45. 6％ for women. The TSH level in MS group was significantly higher than that in non-MS group [(2. 63 ± 1. 01 vs 2. 53 ± 1. 04) mU/ L, P < 0. 01]. Significant differences in BMI, triglycerides(TG), and high density lipoprotein cholesterol(HDL-C) were found in groups with different TSH levels(P<0. 05). The normal TSH level was positively related to TG, fasting insulin,and the prevalence of MS after adjusting for age, BMI, and homeostasis model assessment for insulin resistance ( P < 0. 05). Logistic regression showed that the TSH was an influencing factor for MS(OR=1. 056, 95％ CI 1. 004-1. 111).
