Application of 18 F-FDG PET/ CT in IgG4-related disease
10.3760/cma.j.issn.2095-2848.2018.12.015
- VernacularTitle:18F-FDG PET/CT在IgG4相关性疾病中的临床应用
- Author:
Jie ZHANG
1
;
Xiaoli LAN
Author Information
1. 华中科技大学同济医学院附属协和医院核医学科、分子影像湖北省重点实验室
- Keywords:
Autoimmune diseases;
Immunoglobulin G;
Positron-emission tomography;
Tomography;
X-ray computed;
Deoxyglucose;
Trends
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2018;38(12):824-828
- CountryChina
- Language:Chinese
-
Abstract:
Immunoglobulin (Ig)G4-related disease (IgG4-RD) is a new multi-organ immune-me-diated disease, which was characterized by multiple organs involvement, high serum IgG4 concentrations and IgG4+ plasma cells infiltration. Early diagnosis is helpful for the treatment and prognosis evaluation. Im-aging can provide important diagnostic bases for IgG4-RD, but conventional imaging methods are difficult to determine the overall involvement of the patient. 18 F-fluorodeoxyglucose (FDG) PET/ CT can display the changes of morphology and metabolism in involved organs, and can be used in the diagnosis, guidance of bi-opsy, therapeutic response monitoring and recurrence of IgG4-RD. This review summarizes the applications of 18 F-FDG PET/ CT in patients with IgG4-RD.
