Research status and progress on exosomes in the diagnosis and treatment of malignant glioma
10.3760/cma.j.issn.1004-4221.2018.04.019
- VernacularTitle:外泌体在恶性胶质瘤诊治中的研究现状及进展
- Author:
Shaohua TANG
1
;
Jun YIN
;
Weidong WANG
;
Jinyi LANG
Author Information
1. 646000泸州,西南医科大学临床医学院;610041成都,四川省肿瘤医院·研究所 四川省癌症防治中心放疗科电子科技大学医学院
- Keywords:
Exosomes;
Glioma;
Liquid biopsy;
Prognosis evaluation
- From:
Chinese Journal of Radiation Oncology
2018;27(4):425-429
- CountryChina
- Language:Chinese
-
Abstract:
In recent years,exosomes has gradually captivated widespread attention.It plays a crucial role in the proliferation,differentiation and metastasis of malignant tumors.As nanosized vesicles,exosomes can penetrate through the blood-brain barrier.Thus,exosomes may be a novel tool for the diagnosis and treatment of malignant glioma.In this paper,57 relevant literatures were reviewed to summarize the research status and progress on the role of exosomes in the incidence,progression,liquid biopsy,prognosis evaluation and clinical therapy of malignant glioma.
