Optimization of Extraction Process for Walnut Quinone from Juglans Green Peel by Box-Behnken Response Surface
10.3969/j.issn.1005-5304.2018.07.016
- VernacularTitle:Box-Behnken响应面法优化青龙衣中胡桃醌提取工艺
- Author:
Li-Hong WANG
1
;
Yong-Jie YAN
;
Hong ZHAO
;
Xi-Ming ZONG
;
Yun-Jie ZHANG
Author Information
1. 佳木斯大学药学院
- Keywords:
Juglans green peel;
Box-Behnken response surface methodology;
Juglans mandshurica;
walnut quinone;
extraction process
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2018;25(7):67-70
- CountryChina
- Language:Chinese
-
Abstract:
Objective To optimize extraction process of walnut quinone from Juglans green peel. Methods On the basis of single factor tests, taking material-liquid ratio, extracting temperature and ethanol concentration as independent variables, yield of walnut quinone in response to as a value, according to Box-Behnken experiment design principle, extraction process of walnut quinone from Juglans green peel was optimized by response surface analysis. Results The optimum extraction process of walnut quinone was: 14.30 times the amount of 89.81% ethanol;30.28 ℃ constant temperature. The extracting amount of walnut quinone was 2.034 mg/g, which was close to the experimental results of 1.957 mg/g. Conclusion The optimized extraction process is reasonable and feasible, which can provide reference for the extraction of walnut quinone from Juglans green peel.
