Progress in Vascular Dementia Rat Model Induced by Bilateral Common Carotid Artery Ligation(review)
10.3969/j.issn.1006-9771.2018.03.012
- VernacularTitle:双侧颈总动脉结扎致血管性痴呆大鼠模型研究进展
- Author:
Min MENG
1
;
Lin LI
Author Information
1. 首都医科大学宣武医院药物研究室
- Publication Type:Journal Article
- Keywords:
vascular dementia;
bilateral common carotid artery ligation;
cognitive function;
neuron;
synapse;
neuroin-flammation;
rats;
review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2018;24(3):309-312
- CountryChina
- Language:Chinese
-
Abstract:
Rats after permanent bilateral common carotid artery ligation would result in cerebral blood flow reduction,learning and memory dysfunction,neuronal injury and death,synaptic and dendritic injury,and neuroinflammation,etc.,which repro-duce the pathology and clinical symptoms of human vascular dementia,that help for further research on pathophysiolo-gy and treatment of vascular dementia.
