Comparison of the effects of urethral resection and open operation in the treatment of early bladder cancer
10.3760/cma.j.issn.1008-6706.2018.22.020
- VernacularTitle:经尿道电切术与开放手术治疗早期膀胱癌的临床效果比较
- Author:
Wei ZHOU
1
;
Zhechao WAN
Author Information
1. 诸暨市中心医院泌尿外科
- Keywords:
Urinary bladder neoplasms;
Cystectomy;
Postoperative complications;
Quality of life;
Survival rate;
Controlled clinical trial
- From:
Chinese Journal of Primary Medicine and Pharmacy
2018;25(22):2939-2943
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the effect and prognosis of transurethral resection and open surgery in the treatment of early bladder cancer. Methods From January 2010 to January 2013,76 patients with early bladder cancer in Zhuji Central Hospital were selected in the research. According to the operation method,the patients were divided into the transurethral resection group(42 patients) and open group(34 patients). Transurethral resection of the prostate was performed in the transurethral resection group. The open group underwent open surgery. The operative parameters,postoperative complications,postoperative quality of life and 3 - year survival rate were observed in the two groups. Results The operation time of the transurethral resection group was (28. 96 ± 8. 65)min,which was shorter than (41. 03 ± 10. 22) min of the open group(t = 5. 576,P = 0. 000). The operative blood loss of the transurethral resection group was (30. 62 ± 8. 28)mL,which was lower than (106. 54 ± 6. 44)mL of the open group(t = 43. 789, P = 0. 000). The indwelling catheter time,out of bed time,length of hospital stay in the transurethral resection group were (2. 03 ± 0. 19)d,(13. 54 ± 4. 19)h,(5. 67 ± 1. 16)d,respectively,which were shorter than those in the open group [(2. 86 ± 0. 26) d,(34. 76 ± 5. 23) h,(12. 30 ± 2. 53) d,t = 16. 066,19. 644,15. 147,P = 0. 000,0. 000, 0. 000). The incidence rate of postoperative complications in the transurethral resection group was 45. 24％ ,which was significantly higher than 11. 76％ in the open group. The highest complication rate was transurethral resection syndrome,accounting for 33. 33％ . The open group had the highest incidence of urethral stricture,accounting for 8. 82％ . There were no statistically significant differences in IPSS score,QOL score,Qmax and PVR between the two groups after 1 year (all P > 0. 05). The 3 - year survival rate of the transurethral resection group was 80. 95％ ,which was slightly higher than 61. 76％ in the open group,but there was no statistically significant difference (P > 0. 05). There was no significant difference in the survival time between the two groups (P > 0. 05). Conclusion Transurethral resection and open surgery for early bladder cancer patients have no significant influence on long - term survival quality and survival time, but the transurethral resection has high incidence of postoperative complications, open surgery has slow recovery, two methods have advantages and disadvantages, we should choose proper operation according to the specific situation of patients.
