Efficacy and economic evaluation of sequential levofloxacin therapy in elderly patients with acute pneumonia
10.3760/cma.j.issn.1008-6706.2018.16.005
- VernacularTitle:左氧氟沙星序贯治疗老年人急性肺炎的疗效与经济学评价
- Author:
Aiping XUE
1
Author Information
1. 西山煤电职工总医院杜儿坪分院内科
- Keywords:
Pneumonia;
Economics,pharmaceutical;
Levofloxacin;
Aged
- From:
Chinese Journal of Primary Medicine and Pharmacy
2018;25(16):2057-2060
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical efficacy and pharmacoeconomicvalue of levofloxacin in the treatment of acute pneumonia.Methods From March 2015 to March 2016,120 elderly patients with acute pneumonia in Xishan Coal Worker General Hospital were selected as the research objects,and they were randomly divided into A,B,C three groups according to the envelope method,with 40 cases in each group.A group took levofloxacin injection intravenous oral sequential-levofloxacin tablets.B group took the levofloxacin Injection continuous intravenous infusion therapy.C group took moxifloxacin sodium chloride injection continuous intravenous infusion treatment effect of the three groups were compared the clinical efficacy and cost ratio.Results There was no statistically significant difference in treatment course among the three groups (P ＞ 0.05);The total effective rate of A,B,C three groups was 82.50％,82.50％,80.00％,respectively,there was no statistically significant difference among the three groups (x2 =0.2133,P ＞ 0.05);The cost effectiveness ratio of A group was 11.21,which in B group was 17.31,which in C group was 33.65,the cost effectiveness ratio of A group was significantly better than that of B group and C group (x2 =5.235,5.982,all P ＜ 0.05).Conclusion The sequential treatment with levofloxacin injection can achieve good curative effect and lower economic cost for elderly patients with acute pneumonia.
