Effect of Guilongkechuanning combined with cefotaxime in the treatment of elderly patients with acute exacerbation of chronic bronchitis
10.3760/cma.j.issn.1008-6706.2018.12.004
- VernacularTitle:桂龙咳喘宁联合头孢噻肟治疗老年人慢性支气管炎急性发作的疗效观察
- Author:
Yahong WANG
1
Author Information
1. 315700,浙江省象山县第三人民医院综合科
- Keywords:
Bronchitis;
Chronic disease;
Guilongkechuanning;
Cefotaxime;
Aged;
Respiratory function tests;
Comparative effectiveness research
- From:
Chinese Journal of Primary Medicine and Pharmacy
2018;25(12):1510-1513
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effect of Guilongkechuanning combined with cefotaxime in the treatment of elderly patients with acute exacerbation of chronic bronchitis .Methods 68 patients with acute exacerbation of chronic bronchitis were selected from April 2016 to March 2017 in the Third People's Hospital of Xiangshan County,and they were randomly divided into control group and observation groupaccording to the digital table,with 34 cases in each group .The two groups were given symptomatic treatment , the control group received cefotaxime treatment, while the observation group was given cefotaxime combined with Guilongkechuanning .The clinical effect , symptoms improve time , hospitalization time and lung function were observed in the two groups .Results The total effective rate of the observation group was 94.12％,which was significantly higher than 76.47％of the control group (χ2 =4.22,P<0.05).The recovery time of sputum,cough,wheezing and,hospitalization time in the observation group were (3.09 ±0.76)d,(4.28 ±0.83)d,(4.30 ±0.92)d,(7.02 ±0.66)d,respectively,which were significantly shorter than those in the control group [(5.93 ±0.60) d,(8.34 ±0.56) d,(9.19 ±1.05) d, (10.54 ±1.03)d](t=17.10,23.64,20.42,16.78,all P<0.05).After treatment,the forced vital capacity,forced expiratory volume in one second and forced vital capacity ratio in the observation group were (3937.48 ±18.99)mL, (64.28 ±3.45)％,respectively,which were better than those in the control group [(3038.42 ±20.31) mL, (57.88 ±2.89)％](t=188.54,8.29,all P<0.05).Conclusion Guilongkechuanning combined with cefotaxime in the treatment of elderly patients with acute exacerbation of chronic bronchitis has definite effect , which can effectively control the disease .
