Focus on the clinical application of limbal stem cells
10.3760/cma.j.issn.2095-0160.2018.11.002
- VernacularTitle:努力开创角膜缘干细胞临床研究新局面
- Author:
Zuguo LIU
1
;
Guoliang WANG
;
Cheng LI
Author Information
1. 361102,厦门大学眼科研究所 厦门大学附属翔安医院 厦门大学附属厦门眼科中心 福建省眼科与视觉科学重点实验室
- Keywords:
Limbal stem cells;
Immunologic rejection;
Niche
- From:
Chinese Journal of Experimental Ophthalmology
2018;36(11):822-825
- CountryChina
- Language:Chinese
-
Abstract:
Limbal stem cells (LSCs) transplantation is an effective surgical treatment to address limbal stem cells deficiency ( LSCD) resulting from Stevens Johnson's syndrome or corneal chemical burn. LSCs transplantation has been reported as the successful stem cell therapy for bodybuilding, while it still faces a number of daunting challenges. Researchers should pay more attention to substitute seed cell, novel cell carrier materials, effective expansion method,niche modification and immune rejection,so that patients with ocular surface diseases would get fullly therapeutic benefit.
