Role of acute hypervolemic hemodilution with controlled hypotension and autologous blood transfusion on spinal surgery
10.7652/jdyxb201804022
- VernacularTitle:急性高容量血液稀释联合控制性降压及自体血回输在骨科脊柱手术中的应用
- Author:
Rui WANG
1
;
Shao-Shuang WANG
;
Wei WANG
Author Information
1. 西安交通大学第一附属医院麻醉科
- Keywords:
acute hypervolemic hemodilution;
controlled hypotension;
autologous blood transfusion;
spinal surgery;
hemodynamics;
regional cerebral oxygen saturation(rSO2)
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2018;39(4):558-561
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy and safety of acute hypervolemic hemodilution (AHH) in combination with controlled hypotension (CH)and autologous blood transfusion (ABT)on spinal surgery. Methods For this study,we enrolled 50 patients undergoing spinal surgery and randomly divided them into two groups.The experimental group received AHH in combination with CH and ABT,while the control group received none of the above treatments.We compared the parameters such as hemodynamics,blood routine and coagulation, the amount of intraoperative bleeding,autologous and allogeneic blood transfusion volume,and regional cerebral oxygen saturation (rSO2)between the two groups.Results In the experimental group CVP increased,while invasive artery blood pressure, HCT, Hb, PLT and the amount of allogeneic blood transfusion decreased significantly compared with those of the control group (P＜0.05).As for the mean intraoperative blood loss, APTT,PT,TT,FIB and rSO2,there were no significant differences between the two groups (P＞0.05). Conclusion AHH in combination with CH and ABT can reduce the amount of allogeneic blood transfusion and has no adverse effect on hemodynamics,blood coagulation or cerebral oxygenation in spinal surgery patients.It is a safe and effective blood protection procedure during spinal surgery.
