Overview and considerations on MRI research of neonatal punctate white matter lesions
10.7652/jdyxb201802001
- VernacularTitle:新生儿局灶性白质损伤的MRI研究现状及其核心问题的思考
- Author:
Jian YANG
1
;
Xian-Jun LI
Author Information
1. 西安交通大学第一附属医院医学影像科
- Keywords:
neonatal punctate white matter lesion;
brain function and structure;
degeneration pattern;
individualized diagnosis;
early prediction
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2018;39(2):153-159
- CountryChina
- Language:Chinese
-
Abstract:
The number of preterm neonates appears to remain high in China in recent years.These subjects are vulnerable to pathogenic factors and have brain lesions easily.Punctate white matter lesions(PWML)are very common(the incidence>20%).The degeneration in the brain associated with PWML is harmful to the outcomes and hard to be detected.Early diagnosis and prediction of PWML are focuses for pediatric researchers.This paper describes the change patterns and spatial distributions associated with PWML.The factors of individual differences and development during the diagnosis and prognosis are discussed as well.Finally,the paper points out the core problems in developmental brain template construction,individualized diagnosis,and early prediction.