Clinical characteristics of non-steroidal anti-inflammatory drugs induced peptic ulcer bleeding
10.3969/j.issn.1006-5725.2018.09.026
- VernacularTitle:非甾体类抗炎药相关性消化性溃疡出血的临床分析
- Author:
Jianfeng FENG
1
;
Qingshan ZHAO
Author Information
1. 台山市人民医院消化科 广东台山 529200
- Keywords:
non-steroidal anti-inflammatory drugs;
peptic ulcer bleeding;
endoscopic characteristics;
clinical feature
- From:
The Journal of Practical Medicine
2018;34(9):1513-1515
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical characteristics of non-steroidal anti-inflammatory drugs (NSAIDs)induced peptic ulcer bleeding(PUB). Methods The case-control study was used to analyze the clinical data of 142 patients with NSAIDs-induced PUB and 210 patients with non-NSAIDs-induced PUB. Results There were significant differences between the two groups regarding sex and age of patient,history of rheumatic diseases or cardio-cerebral-vascular disease,types and numbers of ulcer,abdominal pain,hemoglobin concentration,and hospital stay(P<0.05),but there was no obvious difference in terms of the size of ulcer,BUN and HP infection rate. Conclusion Proper measures should be employed to decrease the complications of NSAIDs-induced PUB.