The factor analysis of chemotherapy related symptoms among patients with gastrointestinal cancer
10.3760/cma.j.issn.1672-7088.2018.05.001
- VernacularTitle:FOLFOX6化疗方案消化道癌症患者症状群的分析
- Author:
Aijun WANG
1
;
Kefang WANG
Author Information
1. 山东大学齐鲁医院化疗科
- Keywords:
Symptoms clusters;
Chemotherapy;
Gastrointestinal cancer;
Influencing factor
- From:
Chinese Journal of Practical Nursing
2018;34(5):321-325
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the status and influencing factors of symptom clusters in patients with gastrointestinal cancer receiving FOLFOX6 chemotherapy. Methods Totally 100 patients with gastrointestinal cancer receiving FOLFOX6 chemotherapy were investigated using MD. Anderson Symptom Inventory-Chinese (MDASI-C) and Social Support Rating Scale (SSRS). Results The top incidences and severity of symptoms was lack of appetite.Exploratory factor analysis showed three main symptom clusters: gastrointestinal symptom clusters, physical symptom clusters and mental symptom clusters. The number of courses of chemotherapy was the influencing factor of gastrointestinal symptom clusters, physical symptom clusters. For mental symptom clusters, social support was the influencing factor. Conclusions Patients with gastrointestinal cancer suffer from multiple symptoms during FOLFOX6 chemotherapy. The results are good for establishing early predictions of symptoms and providing scientific evidence for the interventions of symptoms clusters.
