Relationship between Red Blood Cell Distribution Width and Severity of Rheumatiod Arthritis
10.3969/j.issn.1671-7414.2018.01.040
- VernacularTitle:红细胞分布宽度与类风湿关节炎疾病程度的关系研究
- Author:
Hua-Jun XIA
1
;
Ying ZHANG
Author Information
1. 温州市中西医结合医院检验科
- Keywords:
red blood cell dirtribution width;
rheumatiod arthritis;
erythrocyte sedimentation rate;
high sensitivity C-reactive protein;
rheumatoid factor
- From:
Journal of Modern Laboratory Medicine
2018;33(1):151-153
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between red blood cell distribution width(RDW) and disease degree of aheumatiod arthritis(RA).Methods Selected 102 RA patients in Department of Rheumatology,the First Affilicated Hospital of Yangtze University from January 2013 to December 2016,and collected the clinical datas and the levels of RDW,erythrocyte sedimentation rate (ESR),high-sensitivity C-reactive protein (hs-CRP) and rheumatoid factor (RF).The patients were divided into high inflammatory and low inflammatory groups on the basis of ESR (40 mm/h) and hs-CRP (5 mg/L),and also were divided into nonanemic and anemic groups on the basis of HB (110 g/L).The differences of various factors among groups were evaluated by t test and relations between various factors were evaluated by Spearman correlation analysis.Results ①The levels of ESR,hs-CRP and RF were very high in RA patients.②RDW and RF levels were higher but HB and RBC were lower in high inflammatory groups than in low inflammatory (P＜0.05).RDW,RF,ESR and hs-CRP levels in anemic groups were higher than in nonanemic groups (P＜0.05).③RDW was significantly associated with ESR,hs CRP and RF in all RA patients,but was no associated with ESR,hs-CRP and RF in nonanemic groups.Conclusion RDW was associated with the severity of disease and inflammatory factors in RA,but the relationship may be affected by anemia.
