Evaluation on the Accuracy of VITEK 2 Compact for the Susceptibility of Carbapenem-Resistant Klebsiella Peumoniae to Amikacin

VernacularTitle:VITEK 2 Compact检测耐碳青霉烯类肺炎克雷伯菌对阿米卡星药敏结果的准确性评价
Author: Yun LIU ¹ ; Yu-Xiang WAN ; Wei MA ; Ya-Zhou LI ; Xiao-Chun HUANG ; Qin QIN
Author Information

1. 海军军医大学第一附属医院实验诊断科
Keywords: VITEK 2 compact; carbapenem-resistant klebsiella peumoniae (CRKP); amikacin; K-B method; E-test method
From: Journal of Modern Laboratory Medicine 2018;33(1):133-136
CountryChina
Language:Chinese
Abstract: Objective To evaluate the accuracy of VITEK 2 Compact in the detection of the drug susceptibility of carbapenemresistant Klebsiella pneumoniae (CRKP) to Amikacin.Methods The susceptibility for 147 isolates of SRKP to Amikacin were detected by VITEK 2 Compact,disk diffusion method (K-B method) and E-test method,respectively.Results Among the 147 strains of Klebsiella pneumoniae,the drug susceptibility results were consistent between K B and E-test method.Among the 5 strains,the results were totally consistent by VITEK 2 Compact,K-B method and E test method,of which 4 strains were sensitive,1 strains were resistant.There were 142 strains being not consistent between VITEK 2 Compact and E-test method.The results of VITEK 2 Compact were sensitive or intermediate,while E test were drug resistance.Conclusion VITEK 2 Compact is not reliable for the detection of CRKP to Amikacin,which requires that K B method or other methods should be used for the susceptibility of CRKP to Amikacin.