Research Approaches on Discovery R&D of Innovative Drug of Chinese Materia Medica under New Situations
- VernacularTitle:再议新形势下中药创新药物的发现与研发思路
- Author:
Yong JIANG
1
;
Jun LI
;
Pengfei TU
Author Information
- Keywords: Innovative drug of Chinese materia medica; new drug of active component; new drug of effective fraction; famous classic prescription; research approach; pharmaceutical research
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2017;19(6):892-899
- CountryChina
- Language:Chinese
- Abstract: In recent years,with the rapid development of life sciences,changes on the understanding and requirements for innovative drugs of Chinese materia medica (CMM) from the drug approval authorities have been made.In this paper,the discovery,research and development (R & D) approaches for innovative drugs of CMM under new situations were summarized and introduced in details from five aspects as follows.The discovery of innovative drugs from active components of CMMs,active fractions of CMMs and their compound preparations,famous classic prescription,clinically effective prescriptions as well as the famous Chinese patent drugs.This paper puts forward some new ideas for the pharmaceutical researches of innovative drugs of CMM,including the production process,chemical components,quality study,quality standard and stability.This paper provided references for the discovery,R & D of CMM.
