Clinical features of three pulmonary alveolar proteinosis patients
10.3969/j.issn.1000-3606.2018.02.003
- VernacularTitle:肺泡蛋白沉积症3例临床分析
- Author:
Yanhong HUANG
1
;
Donghong PENG
Author Information
1. 重庆医科大学附属儿童医院 国家住院医师规范化培训示范基地 儿童发育疾病研究教育部重点实验室 儿科学重庆市重点实验室 重庆市国际科技合作基地 重庆 400014
- Keywords:
pulmonary alveolar proteinosis;
bronchoalveolar lavage;
PAS staining
- From:
Journal of Clinical Pediatrics
2018;36(2):91-94
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnosis and treatment of pulmonary alveolar proteinosis (PAP). Methods Clinical data of 3 children with PAP admitted from 2010 to 2016 were retrospectively analyzed. Results Three children were female and aged 3 years and 1 month, 3 years and 9 months, and 6 years and 4 months, respectively. The main symptom of the three children was cough along with or without anhelation. Two of them had longer course of disease. The therapeutic effect of conventional treatment was poor, and their chest CT indicated significant lesions. Fiberoptic bronchoscopy showed positive reaction by PAS staining, and the treatment effect was improved after bronchoalveolar lavage. Conclusions The main clinical symptoms of PAP are non-specific cough and shortness of breath. PAS staining and bronchoalveolar lavage are of great value in the diagnosis and treatment of PAP.
