The Progress of IL-10 and Autoimmune Diseases
10.3969/j.issn.1003-4706.2018.02.001
- VernacularTitle:IL-10与自身免疫病的研究进展
- Author:
Mo CHEN
1
Author Information
1. 昆明医科大学第二附属医院血液科
- Keywords:
Interleukin-10;
Immune regulation;
Autoimmune diseases
- From:
Journal of Kunming Medical University
2018;39(2):1-4
- CountryChina
- Language:Chinese
-
Abstract:
Interleukin-10 (IL-10),a single strand glycoprotein,is produced by both adaptive and innate immune cells. IL-10 specific receptor as a complex consists of two submits IL-10R1 and IL-10R2. IL-10 mainly plays biological functions via JAK-STAT signaling pathway. IL-10 is a crucial anti-inflammation cytokine taking part in immune regulation and having significant effect on autoimmune diseases. This paper reviews the relationships be-tween IL-10 and autoimmune diseases according to research achievements in recent years.
